Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 4/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27247726 | 1.00 | GRM5 (0.34) | GRM5SMN1; SMN2EGFRMGLLERBB2 | |
| SCHEMBL27247173 | 0.92 | SMN1; SMN2 (0.35) | GRM5SMN1; SMN2EGFRMGLLERBB2 | |
| SCHEMBL30920271 | 0.92 | SMN1; SMN2 (0.35) | GRM5SMN1; SMN2EGFRMGLLERBB2 | |
| SCHEMBL27247555 | 0.92 | GRM5 (0.35) | GRM5SMN1; SMN2EGFRMGLLERBB2 | |
| SCHEMBL30920320 | 0.92 | GRM5 (0.35) | GRM5SMN1; SMN2EGFRMGLLERBB2 | |
| SCHEMBL30920477 | 0.91 | GRM5 (0.35) | GRM5SMN1; SMN2EGFRMGLLERBB2 | |
| SCHEMBL27247265 | 0.91 | GRM5 (0.35) | GRM5SMN1; SMN2EGFRMGLLERBB2 | |
| SCHEMBL30920912 | 0.90 | KDM1A (0.33) | SMN1; SMN2MGLLPDE10AMAPK1SCD | |
| SCHEMBL27247360 | 0.90 | KDM1A (0.33) | SMN1; SMN2MGLLPDE10AMAPK1SCD | |
| SCHEMBL30946117 | 0.89 | GRM5 (0.37) | GRM5SMN1; SMN2EGFRMGLLERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | HERCULES CAPITAL, INC., AS AGENT | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | SLC6A19, SLC2A9, SLC6A3 | GRM5 690/4885SMN1; SMN2 375/4885EGFR 2037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.