Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.51 |
| ▸ | KISS1R | Q969F8 | 6/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 2/20 | 0.48 |
| ▸ | NPY2R | P49146 | 2/20 | 0.48 |
| ▸ | NPY4R | P50391 | 2/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945347 | 0.94 | MAGI3 (0.52) | MAGI3KISS1RACEERAP2NPY1R | |
| SCHEMBL30945346 | 0.93 | MAGI3 (0.52) | MAGI3KISS1RACENPY1RNPY2R | |
| SCHEMBL30093131 | 0.93 | MAGI3 (0.52) | MAGI3KISS1RACEERAP2NPY1R | |
| SCHEMBL30148460 | 0.91 | KISS1R (0.54) | MAGI3KISS1RACEPRMT1NPY1R | |
| SCHEMBL29732610 | 0.91 | KISS1R (0.54) | MAGI3KISS1RACEPRMT1NPY1R | |
| SCHEMBL31110538 | 0.91 | KISS1R (0.54) | MAGI3KISS1RACEPRMT1NPY1R | |
| SCHEMBL30339696 | 0.91 | KISS1R (0.54) | MAGI3KISS1RACEPRMT1NPY1R | |
| SCHEMBL30305295 | 0.91 | KISS1R (0.54) | MAGI3KISS1RACEPRMT1NPY1R | |
| SCHEMBL31064875 | 0.91 | KISS1R (0.55) | MAGI3KISS1RERAP2MMP1 | |
| SCHEMBL30092955 | 0.91 | ACE (0.54) | MAGI3KISS1RACEPRMT1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11975040-B2 | Plexin binding regulator | THE UNIVERSITY OF TOKYO (JP) | 2024-05-07 | — | — | US | disclosed |
| US-11975040-B2 | Plexin binding regulator | THE UNIVERSITY OF TOKYO (JP) | 2024-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11975040-B2 | Plexin binding regulator | TEK, SERBP1, LRRFIP1 | MAGI3 3754/4885KISS1R 1802/4885ACE 4660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.