Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | BACE1 | P56817 | 10/20 | 0.52 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798078 | 0.92 | OPRD1 (0.59) | OPRD1BACE1BACE2CTSD | |
| SCHEMBL29531717 | 0.91 | BACE1 (0.56) | OPRD1BACE1BACE2NAALAD2OPRM1 | |
| SCHEMBL29532196 | 0.91 | BACE1 (0.56) | BACE1BACE2CTSD | |
| SCHEMBL31062518 | 0.91 | OPRD1 (0.61) | OPRD1BACE1BACE2OPRM1CASP1 | |
| SCHEMBL29458786 | 0.90 | ACE (0.51) | OPRD1BACE1BACE2NAALAD2OPRM1 | |
| SCHEMBL11886068 | 0.90 | ACE (0.51) | OPRD1BACE1BACE2NAALAD2OPRM1 | |
| SCHEMBL29857400 | 0.90 | ACE (0.51) | OPRD1BACE1BACE2NAALAD2OPRM1 | |
| Tyrosine SCHEMBL19809042 | 0.89 | SLC7A5 (0.56) | OPRD1BACE1BACE2NAALAD2 | |
| Tyrosine SCHEMBL19809043 | 0.89 | SLC7A5 (0.56) | OPRD1BACE1BACE2NAALAD2 | |
| SCHEMBL11886066 | 0.88 | NAALAD2 (0.66) | NAALAD2NPY1RNPY2RNPY4RERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108227-A1 | CBX2 INHIBITORY COMPOUNDS FOR TREATING HIGH GRADE SEROUS OVARIAN CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2024-05-23 | — | — | WO | disclosed |