Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293923 | 1.00 | KDM4E (0.47) | KDM4EMAPTTHRBHPGDSCNR1 | |
| SCHEMBL22701202 | 0.94 | HPGDS (0.49) | KDM4EMAPTTHRBHPGDSCNR1 | |
| SCHEMBL20439472 | 0.90 | KDM4E (0.42) | KDM4EMAPTHPGDSROCK2HCAR1 | |
| SCHEMBL7718379 | 0.85 | HPGDS (0.55) | KDM4EMAPTTHRBHPGDSALDH1A1 | |
| SCHEMBL30496019 | 0.85 | HPGDS (0.55) | KDM4EMAPTTHRBHPGDSALDH1A1 | |
| SCHEMBL23293909 | 0.85 | ROCK2 (0.46) | MAPTROCK2NPSR1 | |
| SCHEMBL12026566 | 0.85 | MAPT (0.47) | KDM4EMAPTTHRBHPGDSCNR1 | |
| SCHEMBL26170074 | 0.83 | NSD2 (0.47) | MAPTCNR1FPR2HTTUSP30 | |
| SCHEMBL30186938 | 0.83 | NSD2 (0.47) | MAPTCNR1FPR2HTTUSP30 | |
| SCHEMBL23293951 | 0.83 | KDM4E (0.47) | KDM4EMAPTTHRBHPGDSCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |