Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | LGMN | Q99538 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527712 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2IP6K1GFERGAA | |
| SCHEMBL28519359 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2IP6K1GFERGAA | |
| SCHEMBL28519358 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2IP6K1GFERGAA | |
| SCHEMBL28527710 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2IP6K1GFERGAA | |
| SCHEMBL17774925 | 0.85 | NR1I2 (0.43) | IP6K1GFERGAALGMN | |
| SCHEMBL30947754 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL30947741 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL28534786 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL28534785 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL28526591 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |