Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30947761 | 1.00 | SIRT6 (0.53) | SIRT6ALDH1A1MAPTMGLLLMNA | |
| SCHEMBL23316336 | 1.00 | SIRT6 (0.53) | SIRT6ALDH1A1MAPTMGLLLMNA | |
| SCHEMBL28909499 | 1.00 | SIRT6 (0.53) | SIRT6ALDH1A1MAPTMGLLLMNA | |
| SCHEMBL23316424 | 1.00 | SIRT6 (0.53) | SIRT6ALDH1A1MAPTMGLLLMNA | |
| SCHEMBL23316455 | 0.89 | SIRT6 (0.52) | SIRT6ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL23316306 | 0.89 | ALDH1A1 (0.48) | SIRT6ALDH1A1MAPTMGLLLMNA | |
| SCHEMBL28519340 | 0.85 | SIRT6 (0.50) | SIRT6ALDH1A1MAPTMGLLLMNA | |
| SCHEMBL28519341 | 0.85 | SIRT6 (0.50) | SIRT6ALDH1A1MAPTMGLLLMNA | |
| SCHEMBL28533378 | 0.85 | SIRT6 (0.50) | SIRT6ALDH1A1MAPTMGLLLMNA | |
| SCHEMBL29800608 | 0.84 | MAPT (0.50) | SIRT6ALDH1A1MAPTMGLLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |