Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 7/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948277 | 0.98 | IL4I1 (0.72) | IL4I1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27163698 | 0.86 | IL4I1 (1.00) | IL4I1MAPTHTTSMN1; SMN2RXFP1 | |
| SCHEMBL30948292 | 0.84 | IL4I1 (0.80) | IL4I1MAPTSMN1; SMN2RXFP1RAB9A | |
| SCHEMBL30947922 | 0.84 | IL4I1 (0.96) | IL4I1MAPTHTTSMN1; SMN2RXFP1 | |
| SCHEMBL30948229 | 0.84 | IL4I1 (0.79) | IL4I1MAPTSMN1; SMN2RXFP1TP53 | |
| SCHEMBL30948240 | 0.82 | IL4I1 (0.77) | IL4I1MAPTSMN1; SMN2RXFP1RAB9A | |
| SCHEMBL30948130 | 0.82 | IL4I1 (0.63) | IL4I1RXFP1ACKR3TP53LMNA | |
| SCHEMBL30948059 | 0.82 | IL4I1 (0.76) | IL4I1MAPTSMN1; SMN2RXFP1TP53 | |
| SCHEMBL30948288 | 0.79 | IL4I1 (0.96) | IL4I1RXFP1TP53LMNA | |
| SCHEMBL30948149 | 0.78 | IL4I1 (0.69) | IL4I1RXFP1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL2 | IL4I1 1/4885MAPT 3067/4885CYP1A2 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.