Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.81 |
| ▸ | PRKCG | P05129 | 5/20 | 0.81 |
| ▸ | PRKCB | P05771 | 5/20 | 0.81 |
| ▸ | PRKCH | P24723 | 5/20 | 0.81 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.81 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.81 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.81 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.81 |
| ▸ | PRKCI | P41743 | 4/20 | 0.81 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.81 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.81 |
| ▸ | USP2 | O75604 | 2/20 | 0.81 |
| ▸ | TP53 | P04637 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692272 | 0.95 | PRKCA (0.89) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL9306 | 0.95 | PRKCA (0.89) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL6844180 | 0.95 | PRKCA (0.89) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL1893793 | 0.95 | PRKCA (0.89) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| Phorbol Myristate Acetate SCHEMBL6883208 | 0.94 | PRKCA (0.90) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL3211990 | 0.91 | PRKCA (0.94) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL295345 | 0.91 | PRKCA (0.94) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL1568997 | 0.91 | PRKCA (0.94) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL18399995 | 0.90 | PRKCA (0.95) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL2411275 | 0.90 | PRKCA (0.95) | PRKCAPRKCGPRKCBPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7794930-B2 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2010-09-14 | — | — | US | disclosed |
| US-7482126-B2 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds | CONSEJO SUPERIOR DE INVESTIGACOINES CIENTIFICAS (ES) | 2009-01-27 | — | — | US | disclosed |
| US-7482159-B2 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2009-01-27 | — | — | US | disclosed |
| US-20070077590-A1 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds | CANO GARCIA AMPARO | 2007-04-05 | — | — | US | disclosed |
| US-20070065450-A1 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds | CANO GARCIA AMPARO | 2007-03-22 | — | — | US | disclosed |
| US-20070054307-A1 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds | CANO GARCIA AMPARO | 2007-03-08 | — | — | US | disclosed |
| US-20070053891-A1 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds | CANO GARCIA AMPARO | 2007-03-08 | — | — | US | disclosed |
| EP-1109021-B1 | SNAIL, NEW TUMORAL PROGRESSION MARKER AND TARGET PROTEIN OF NEW ANTITUMORAL COMPOUNDS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2004-12-08 | — | — | EP | disclosed |
| US-20040110139-A1 | Modulation of G protein-coupled receptor 3 expression | ISIS PHARMACEUTICALS INC. | 2004-06-10 | — | — | US | disclosed |
| US-20040037832-A1 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds | GARCIA AMPARO CANO (ES) | 2004-02-26 | — | — | US | disclosed |
| US-6617121-B1 | Snail, new tumoral progression marker and target protein of new antitumoral compounds | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2003-09-09 | — | — | US | disclosed |
| EP-1109021-A1 | SNAIL, NEW TUMORAL PROGRESSION MARKER AND TARGET PROTEIN OF NEW ANTITUMORAL COMPOUNDS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2001-06-20 | — | — | EP | disclosed |