Sugi Predict

Sugi Predict / Compounds / SCHEMBL3692272

SCHEMBL3692272

SCHEMBL3692272

CCCCCCCCCC(=O)O[C@@]12[C@H](OC(C)=O)[C@@H](C)[C@@]3(O)[C@@H](C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1C2(C)C

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKCA P17252 6/20 0.89
▸ PRKCG P05129 5/20 0.89
▸ PRKCB P05771 5/20 0.89
▸ PRKCH P24723 5/20 0.89
▸ PRKCE Q02156 5/20 0.89
▸ PRKCQ Q04759 5/20 0.89
▸ PRKCD Q05655 5/20 0.89
▸ PRKD3 O94806 4/20 0.89
▸ PRKCI P41743 4/20 0.89
▸ PRKCZ Q05513 4/20 0.89
▸ PRKD1 Q15139 4/20 0.89
▸ USP2 O75604 2/20 0.89
▸ TP53 P04637 2/20 0.89
▸ KDM4E B2RXH2 1/20 0.89
▸ ALDH1A1 P00352 1/20 0.89
▸ SMN1; SMN2 Q16637 1/20 0.89
▸ CYP3A4 P08684 1/20 0.89
▸ CYP2C9 P11712 1/20 0.89
▸ TSHR P16473 1/20 0.89
▸ NFKB1 P19838 1/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9306 1.00 PRKCA (0.89) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL1893793 1.00 PRKCA (0.89) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL6844180 1.00 PRKCA (0.89) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL3211990 0.95 PRKCA (0.94) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL1568997 0.95 PRKCA (0.94) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL295345 0.95 PRKCA (0.94) PRKCAPRKCGPRKCBPRKCHPRKCE
Phorbol SCHEMBL3094837 0.95 PRKCA (0.81) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL18399995 0.95 PRKCA (0.95) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL2411275 0.95 PRKCA (0.95) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL31109155 0.95 PRKCA (0.95) PRKCAPRKCGPRKCBPRKCHPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702575-A Application of APOL2 inhibitor in preparation of product for treating hepatic fibrosis 中山大学 2024-09-27 — — CN disclosed
US-20180171290-A1 METHOD OF PRODUCING PROGENITOR CELLS FROM DIFFERENTIATED CELLS REGENERTECH PTY LIMITED (AU) 2018-06-21 — — US disclosed
US-20120121546-A1 Method of Producing Progenitor Cells from Differentiated Cells BHASIN VISHAL (NZ) 2012-05-17 — — US disclosed
WO-2010088735-A1 METHOD OF PRODUCING PROGENITOR CELLS FROM DIFFERENTIATED CELLS REGENERTECH PTY LTD (AU) 2010-08-12 — — WO disclosed
WO-2004007445-A2 PROTEIN KINASE C MODULATORS, AND METHODS OF USE THEREOF GEORGETOWN UNIVERSITY (US) 2004-01-22 — — WO disclosed
US-6268395-B1 FOR EXAMPLE ANTI-HIV AGENT; HAVING HIGHER ANTIVIRAL EFFECTS AND LESS DELETERIOUS SIDE EFFECTS AS COMPARED WITH CONVENTIONALLY KNOWN ANTIVIRAL AGENTS. LEAD CHEMICAL CO., LTD. (JP) 2001-07-31 — — US disclosed
WO-1988003030-A1 METHOD FOR INDUCING ENDOGENOUS PRODUCTION OF TISSUE PLASMINOGEN ACTIVATOR (tPA) MOSCATELLI DAVID A (US) 1988-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120121546-A1 Method of Producing Progenitor Cells from Differentiated Cells ALPG, MYADM, KIT PRKCA 1370/4885PRKCG 1091/4885PRKCB 1378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.