Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 15/20 | 0.66 |
| ▸ | IGF1R | P08069 | 15/20 | 0.66 |
| ▸ | ALK | Q9UM73 | 15/20 | 0.66 |
| ▸ | EGFR | P00533 | 7/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.59 |
| ▸ | AURKA | O14965 | 2/20 | 0.59 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.59 |
| ▸ | JAK2 | O60674 | 2/20 | 0.59 |
| ▸ | STK10 | O94804 | 2/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.59 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 2/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.59 |
| ▸ | LCK | P06239 | 2/20 | 0.59 |
| ▸ | FYN | P06241 | 2/20 | 0.59 |
| ▸ | FES | P07332 | 2/20 | 0.59 |
| ▸ | CSF1R | P07333 | 2/20 | 0.59 |
| ▸ | YES1 | P07947 | 2/20 | 0.59 |
| ▸ | LYN | P07948 | 2/20 | 0.59 |
| ▸ | RET | P07949 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29253683 | 1.00 | INSR (0.66) | INSRIGF1RALKEGFRCHEK1 | |
| SCHEMBL27360981 | 0.92 | ALK (0.77) | INSRIGF1RALKEGFRCHEK1 | |
| SCHEMBL19288549 | 0.88 | INSR (0.85) | INSRIGF1RALKEGFRCHEK1 | |
| SCHEMBL29253661 | 0.87 | ALK (0.68) | INSRIGF1RALKEGFRCHEK1 | |
| SCHEMBL25159176 | 0.87 | EGFR (0.63) | INSRIGF1RALKEGFRCHEK1 | |
| SCHEMBL22520175 | 0.87 | ALK (0.85) | INSRIGF1RALKEGFRCHEK1 | |
| SCHEMBL29253697 | 0.87 | ALK (0.68) | INSRIGF1RALKEGFRCHEK1 | |
| SCHEMBL30364542 | 0.85 | EGFR (0.80) | INSRIGF1RALKEGFRCHEK1 | |
| SCHEMBL21558123 | 0.84 | EGFR (0.68) | INSRIGF1RALKEGFRMAPK3 | |
| SCHEMBL24179052 | 0.84 | INSR (0.69) | INSRIGF1RALKEGFRCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677680-B | EGFR inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |