Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 20/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224174 | 0.83 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL1877085 | 0.83 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL1060281 | 0.83 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL15667928 | 0.81 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL1840824 | 0.81 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL27957684 | 0.78 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL12198758 | 0.78 | L3MBTL1 (0.43) | SLC6A2SLC6A4 | |
| SCHEMBL10777585 | 0.76 | L3MBTL1 (0.45) | SLC6A2SLC6A4 | |
| SCHEMBL14224188 | 0.75 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3805861 | 0.75 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598535-A2 | INHIBITORS OF SPNS2 AND USES THEREOF | New York University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076610-A2 | INHIBITORS OF SPNS2 AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |