SCHEMBL1060281

SCHEMBL1060281

CCN(C(C)=O)C1CCNC1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 20/20 0.51
SLC6A2 P23975 19/20 0.51
SLC6A3 Q01959 10/20 0.51
KCNH2 Q12809 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1877085 1.00 SLC6A4 (0.51) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL14224174 1.00 SLC6A4 (0.51) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL16104131 0.89 SLC6A2 (0.46) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL297266 0.89 SLC6A4 (0.49) SLC6A4SLC6A2SLC6A3KCNH2
Hydrochloric Acid SCHEMBL3740415 0.87 SLC6A4 (0.48) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL15667928 0.87 SLC6A2 (0.52) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL1840824 0.87 SLC6A2 (0.52) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL10653802 0.86 SLC6A4 (0.54) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL27957684 0.84 SLC6A2 (0.50) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL30948823 0.83 SLC6A2 (0.50) SLC6A4SLC6A2SLC6A3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113179590-A Etching solution, replenishment solution, and method for forming copper wiring MEC股份有限公司 2021-07-27 CN disclosed
CN-107208279-B Etching solution, replenishment solution, and method for forming copper wiring MEC股份有限公司 2021-03-26 CN disclosed
US-10174428-B2 Etchant, replenishment solution and method for forming copper wiring MEC COMPANY LTD. (JP) 2019-01-08 US disclosed
US-10144849-B2 Polishing composition and polishing method using the same FUJIMI INCORPORATED (JP) 2018-12-04 US disclosed
US-20170260632-A1 ETCHANT, REPLENISHMENT SOLUTION AND METHOD FOR FORMING COPPER WIRING MEC COMPANY LTD. (JP) 2017-09-14 US disclosed
EP-3008055-B1 TETRAZOLONE DERIVATIVES HOFFMANN LA ROCHE (CH) 2017-07-19 EP disclosed
CN-102884062-B Aminopyrimidine inhibitors of kinases 嘉世高制药公司 2016-08-03 CN disclosed
CN-103930426-B As [1,2,3] triazols [4, the 5-D] pyrimidine derivatives of Cannabined receptor 2 activators HOFFMAN-LA ROCHE LTD. (CH) 2016-05-11 CN disclosed
EP-3008055-A1 NOVEL TETRAZOLONE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2016-04-20 EP disclosed
EP-2247588-B1 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL (JP) 2016-04-13 EP disclosed
US-7238709-B2 Therapeutic carbamates THERAVANCE, INC. (US) 2007-07-03 US disclosed
US-7223788-B2 therapy for eating disorders, anorexigenic agents, antidiabetic agents, reducing weight in mammals, circadian rhythm disease, psychological disorders SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-05-29 US disclosed
US-7129247-B2 Aryl phenylheterocyclyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-suppressive agents ABBOTT LABORATORIES (US) 2006-10-31 US disclosed
EP-1643998-A1 DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA F. HOFFMANN-LA ROCHE AG (CH) 2006-04-12 EP disclosed
EP-1597228-A2 SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS Sanofi-Aventis Deutschland GmbH (DE) 2005-11-23 EP disclosed
US-20050090533-A1 Dual NK1/NK3 receptor antagonists F. HOFMANN-LA ROCHE AG (CH) 2005-04-28 US disclosed
US-20050014746-A1 Aryl phenylheterocyclyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-supressive agents ICOS CORPORATION 2005-01-20 US disclosed
WO-2005002577-A1 DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA F. HOFFMANN-LA ROCHE AG (CH) 2005-01-13 WO disclosed
US-20040220191-A1 Substituted N-aryl heterocycles, process for their preparation and their use as medicaments AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-11-04 US disclosed
WO-2004072025-A2 SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014746-A1 Aryl phenylheterocyclyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-supressive agents ICAM1, VCAM1, CD47 SLC6A4 4150/4885SLC6A2 4393/4885SLC6A3 3521/4885
US-20040220191-A1 Substituted N-aryl heterocycles, process for their preparation and their use as medicaments CYP11B2, CYP11B1, CYP1A1 SLC6A4 1157/4885SLC6A2 792/4885SLC6A3 1729/4885
US-20050090533-A1 Dual NK1/NK3 receptor antagonists TACR2, TAC3, TACR1 SLC6A4 166/4885SLC6A2 181/4885SLC6A3 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.