Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17913534 | 0.78 | AHR (0.35) | AHRCYP2A6 | |
| SCHEMBL18571595 | 0.78 | AHR (0.35) | MEN1KMT2AMAOBAHRCYP2A6 | |
| SCHEMBL18572343 | 0.78 | — | — | |
| SCHEMBL1285478 | 0.75 | ATM (0.50) | MEN1KMT2AMAOBAHRCYP2A6 | |
| SCHEMBL1070189 | 0.74 | CRHBP (0.42) | MEN1KMT2AMAOBCYP1A2CYP2A6 | |
| SCHEMBL23405203 | 0.71 | — | — | |
| SCHEMBL2107267 | 0.69 | CYP1A2 (0.45) | MAOBAHRCYP1A2CYP2A6 | |
| SCHEMBL18571541 | 0.67 | MAOB (0.37) | MAOBAHRCYP2A6 | |
| SCHEMBL18571737 | 0.67 | AHR (0.35) | MEN1KMT2AAHRCYP2A6 | |
| SCHEMBL23404984 | 0.67 | ALDH1A1 (0.33) | MEN1KMT2AMAOBAHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598535-A2 | INHIBITORS OF SPNS2 AND USES THEREOF | New York University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076610-A2 | INHIBITORS OF SPNS2 AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |