SCHEMBL30948866

SCHEMBL30948866

Cn1cc2cc(Cn3nnc4ncc(-c5ccc(P(C)C)cc5)nc43)c(F)cc2n1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MET P08581 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22109306 0.86 MET (0.58) MET
SCHEMBL30948880 0.86 MET (0.58) MET
SCHEMBL22109155 0.84 MET (0.56) MET
SCHEMBL22109154 0.83 MET (0.55) MET
SCHEMBL22109163 0.83 MET (0.56) MET
SCHEMBL30948858 0.83 MET (0.56) MET
SCHEMBL22109381 0.82 MET (0.53) MET
SCHEMBL22109382 0.80 MET (0.53) MET
SCHEMBL2568920 0.75 MET (1.00) MET
SCHEMBL22109505 0.73 MET (0.33) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113412112-B Organophosphorus substituted compounds as c-MET inhibitors and therapeutic uses thereof 贝达医药公司 2024-06-11 CN disclosed