Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 3/20 | 0.44 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009138 | 0.85 | PKN2 (0.54) | ASIC3PKN2 | |
| SCHEMBL1010614 | 0.85 | ASIC3 (0.61) | PDE3BPDE3AASIC3PKN2 | |
| SCHEMBL30833275 | 0.85 | PKN2 (0.54) | ASIC3PKN2 | |
| SCHEMBL29543554 | 0.79 | TYRO3 (0.50) | MAPTASIC3 | |
| SCHEMBL8676339 | 0.79 | TYRO3 (0.50) | MAPTASIC3 | |
| SCHEMBL31070593 | 0.78 | CYP11B1 (0.63) | PDE3BPDE3ACYP3A4CYP11B2 | |
| SCHEMBL3875636 | 0.78 | DYRK1A (0.49) | ASIC3CYP3A4DYRK1A | |
| SCHEMBL29543449 | 0.78 | ASIC3 (0.50) | ASIC3 | |
| SCHEMBL22638762 | 0.78 | CYP2D6 (0.49) | ASIC3CYP3A4CYP11B2 | |
| SCHEMBL29386484 | 0.78 | CYP2D6 (0.49) | ASIC3CYP3A4CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072398-B | Compounds that inhibit TDG activity | 上海仕谱生物科技有限公司 | 2024-06-11 | — | — | CN | disclosed |