Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 14/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 14/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TDP2 | O95551 | 2/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009727 | 0.87 | CYP11B1 (0.65) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL1012895 | 0.87 | CYP11B2 (0.65) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL30948932 | 0.78 | PDE3B (0.50) | CYP11B2CYP3A4PDE3BPDE3A | |
| SCHEMBL8676339 | 0.77 | TYRO3 (0.50) | TDP2ALDH1A1MEN1 | |
| SCHEMBL29543554 | 0.77 | TYRO3 (0.50) | TDP2ALDH1A1MEN1 | |
| SCHEMBL8081400 | 0.77 | CYP11B2 (1.00) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL23137953 | 0.74 | CLK4 (0.69) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL6188859 | 0.73 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL20178628 | 0.73 | CYP11B2 (0.59) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL6187188 | 0.73 | CYP11B1 (0.65) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |