SCHEMBL30949320

SCHEMBL30949320

Cc1cccc(C(=O)Nc2ccc(Oc3ccc4c(c3)C(=O)NC4=O)cc2)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.76
MEN1 O00255 7/20 0.61
HPGD P15428 3/20 0.61
TSHR P16473 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
POLB P06746 2/20 0.57
RXFP1 Q9HBX9 1/20 0.57
GSK3A P49840 2/20 0.56
GSK3B P49841 2/20 0.55
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
TP53 P04637 1/20 0.54
MAPT P10636 2/20 0.53
HTT P42858 1/20 0.53
USP2 O75604 1/20 0.53
ALOX15 P16050 1/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
KCNK3 O14649 1/20 0.51
KCNH2 Q12809 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30949330 0.88 KMT2A (0.81) KMT2AMEN1HPGDTSHRL3MBTL1
SCHEMBL30949328 0.87 RXFP1 (0.76) KMT2AMEN1HPGDTSHRL3MBTL1
SCHEMBL30949348 0.87 GSK3B (0.67) KMT2AMEN1HPGDTSHRL3MBTL1
SCHEMBL30949324 0.86 KMT2A (0.58) KMT2AMEN1HPGDTSHRL3MBTL1
SCHEMBL14542298 0.86 KMT2A (0.72) KMT2AMEN1HPGDTSHRL3MBTL1
SCHEMBL30949343 0.86 KMT2A (0.64) KMT2AMEN1HPGDTSHRL3MBTL1
SCHEMBL30949314 0.83 CASP3 (0.70) KMT2AMEN1HPGDTSHRL3MBTL1
SCHEMBL14560162 0.78 KCNK3 (0.64) KMT2AMEN1L3MBTL1SMN1; SMN2POLB
SCHEMBL30949305 0.76 MEN1 (0.79) KMT2AMEN1HPGDTSHRL3MBTL1
SCHEMBL22984228 0.76 NPC1 (0.59) KMT2AMEN1TSHRL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP claimed
WO-2024153736-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2024-07-25 WO claimed
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP disclosed
WO-2024153736-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2024-07-25 WO disclosed