SCHEMBL30949348

SCHEMBL30949348

O=C(Nc1ccc(Oc2ccc3c(c2)C(=O)NC3=O)cc1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.67
PGR P06401 2/20 0.65
MAOA P21397 1/20 0.65
MAOB P27338 1/20 0.65
CASP3 P42574 2/20 0.64
KMT2A Q03164 7/20 0.64
MEN1 O00255 6/20 0.64
HPGD P15428 3/20 0.64
TSHR P16473 2/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
POLB P06746 1/20 0.60
GSK3A P49840 1/20 0.58
CTDSP1 Q9GZU7 1/20 0.56
RXFP1 Q9HBX9 1/20 0.56
MAPT P10636 2/20 0.56
HTT P42858 1/20 0.56
USP2 O75604 1/20 0.56
ALOX15 P16050 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30949328 0.88 RXFP1 (0.76) GSK3BMAOAMAOBKMT2AMEN1
SCHEMBL30949320 0.87 KMT2A (0.76) GSK3BMAOAMAOBKMT2AMEN1
SCHEMBL30949324 0.87 KMT2A (0.58) GSK3BMAOAMAOBCASP3KMT2A
SCHEMBL30949330 0.86 KMT2A (0.81) GSK3BPGRKMT2AMEN1HPGD
SCHEMBL6264128 0.85 CASP3 (0.86) CASP3KMT2AMEN1POLBCTDSP1
SCHEMBL30949343 0.84 KMT2A (0.64) GSK3BPGRMAOAMAOBKMT2A
SCHEMBL30949314 0.83 CASP3 (0.70) CASP3KMT2AMEN1HPGDTSHR
SCHEMBL8361085 0.82 PGR (0.96) PGRKMT2AMEN1SMN1; SMN2POLB
SCHEMBL30949339 0.81 GSK3B (0.73) GSK3BMAOAMAOBCASP3KMT2A
SCHEMBL30949305 0.81 MEN1 (0.79) GSK3BMAOAMAOBCASP3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP claimed
WO-2024153736-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2024-07-25 WO claimed
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP disclosed
WO-2024153736-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2024-07-25 WO disclosed