SCHEMBL30949335

SCHEMBL30949335

COc1cccc(C(=O)Nc2ccc(Oc3ccccc3)cc2)c1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.87
AR P10275 1/20 0.85
NPC1 O15118 6/20 0.83
RAB9A P51151 6/20 0.83
SMN1; SMN2 Q16637 3/20 0.83
MEN1 O00255 7/20 0.80
KMT2A Q03164 7/20 0.80
TP53 P04637 3/20 0.74
KCNK3 O14649 1/20 0.74
KCNK9 Q9NPC2 1/20 0.74
KDM4E B2RXH2 1/20 0.74
TSHR P16473 1/20 0.74
NFKB1 P19838 1/20 0.74
NFKB2 Q00653 1/20 0.74
RELA Q04206 1/20 0.74
ALDH1A1 P00352 1/20 0.72
PKM P14618 1/20 0.72
HPGD P15428 1/20 0.72
MAPK1 P28482 1/20 0.72
NLRP3 Q96P20 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12167724 0.97 AR (0.89) PGRARNPC1RAB9ASMN1; SMN2
SCHEMBL30949327 0.96 AR (0.87) PGRARNPC1RAB9ASMN1; SMN2
SCHEMBL5226157 0.91 NPC1 (1.00) PGRNPC1RAB9ASMN1; SMN2MEN1
SCHEMBL6802217 0.91 NPC1 (0.83) PGRARNPC1RAB9ASMN1; SMN2
SCHEMBL9240473 0.90 PGR (0.84) PGRARNPC1RAB9ASMN1; SMN2
SCHEMBL30949311 0.89 RAB9A (0.78) PGRARNPC1RAB9ASMN1; SMN2
SCHEMBL12167712 0.89 MEN1 (0.73) PGRARNPC1RAB9ASMN1; SMN2
SCHEMBL5345650 0.89 KMT2A (1.00) PGRARNPC1RAB9ASMN1; SMN2
SCHEMBL12338966 0.87 MEN1 (0.71) PGRARNPC1RAB9ASMN1; SMN2
SCHEMBL7824945 0.87 KMT2A (0.82) PGRARNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP claimed
WO-2024153736-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2024-07-25 WO claimed
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP disclosed
WO-2024153736-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2024-07-25 WO disclosed