Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
| ▸ | HTR2C | P28335 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | HTR2B | P41595 | 1/20 | 0.72 |
| ▸ | HTR3A | P46098 | 1/20 | 0.72 |
| ▸ | CASP6 | P55212 | 1/20 | 0.71 |
| ▸ | CD44 | P16070 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lurosetron SCHEMBL788289 | 1.00 | KCNH2 (0.72) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A | |
| Lurosetron SCHEMBL7291773 | 0.99 | CASP6 (0.72) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A | |
| Lurosetron SCHEMBL7336906 | 0.99 | KCNH2 (0.71) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A | |
| Lurosetron SCHEMBL635328 | 0.95 | KCNH2 (0.66) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A | |
| Lurosetron SCHEMBL7336554 | 0.95 | KCNH2 (0.65) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A | |
| Lurosetron SCHEMBL7282816 | 0.93 | KCNH2 (0.63) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A | |
| Lurosetron SCHEMBL9486016 | 0.93 | KCNH2 (0.63) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A | |
| Lurosetron SCHEMBL7284073 | 0.92 | KCNH2 (0.65) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A | |
| SCHEMBL7285588 | 0.90 | KCNH2 (0.74) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A | |
| SCHEMBL7293493 | 0.88 | KCNH2 (0.72) | KCNH2CYP1A2CYP3A4ADRA2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250288545-A1 | NEOSTIGMINE COMBINATIONS AND COMPOSITIONS | DAS-MG, INC. | 2025-09-18 | — | — | US | disclosed |
| CN-118681024-A | Compositions and methods for treating depression | 才思治疗公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-110719778-B | Compositions and methods for treating depression | 才思治疗公司 | 2024-06-18 | — | — | CN | disclosed |