Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23698345 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL30678551 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL31634097 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL28947208 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL23698869 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL31115548 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL30949546 | 0.81 | TSHR (0.39) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL22103251 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL31417731 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL30884588 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |