Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 7/20 | 0.39 |
| ▸ | FABP3 | P05413 | 3/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949548 | 0.81 | KDM4E (0.44) | TSHRALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL9188696 | 0.81 | SMN1; SMN2 (0.38) | FABP4FABP3FABP5ALDH1A1KDM4E | |
| SCHEMBL29091574 | 0.79 | G6PD (0.38) | TSHRFABP4ALDH1A1KDM4EHPGD | |
| SCHEMBL30615163 | 0.79 | G6PD (0.38) | TSHRFABP4ALDH1A1KDM4EHPGD | |
| SCHEMBL668562 | 0.77 | GRIK1 (0.39) | TSHRFABP4FABP3FABP5ALDH1A1 | |
| SCHEMBL31417805 | 0.77 | KDM4E (0.36) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL29421547 | 0.76 | DPP4 (0.44) | FABP4FABP3FABP5PRKAB2PRKAG1 | |
| SCHEMBL21225332 | 0.76 | DPP4 (0.44) | FABP4FABP3FABP5PRKAB2PRKAG1 | |
| SCHEMBL496918 | 0.75 | SLC9A1 (0.43) | FABP4FABP3FABP5ALDH1A1KDM4E | |
| SCHEMBL3716928 | 0.74 | ALOX5 (0.39) | TSHRFABP4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |