Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931814 | 1.00 | TDP1 (0.55) | TDP1MAPTCLCN2ALDH1A1CDC25B | |
| SCHEMBL11386183 | 0.86 | MAPT (0.46) | TDP1MAPTCLCN2ALDH1A1CDC25B | |
| SCHEMBL1990965 | 0.85 | TDP1 (0.51) | TDP1MAPTCLCN2ALDH1A1CDC25B | |
| SCHEMBL31697231 | 0.85 | TDP1 (0.51) | TDP1MAPTCLCN2ALDH1A1CDC25B | |
| SCHEMBL2817995 | 0.85 | TDP1 (0.66) | TDP1MAPTCLCN2ALDH1A1CDC25B | |
| SCHEMBL17201318 | 0.85 | MAPT (0.66) | TDP1MAPTCLCN2ALDH1A1CDC25B | |
| SCHEMBL8138210 | 0.85 | TDP1 (0.51) | TDP1MAPTCLCN2ALDH1A1CDC25B | |
| SCHEMBL7691123 | 0.85 | MAPT (0.61) | TDP1MAPTCLCN2ALDH1A1CDC25B | |
| SCHEMBL8492183 | 0.84 | POLB (0.42) | TDP1MAPTCLCN2ALDH1A1HPGD | |
| SCHEMBL6136937 | 0.84 | ALDH1A1 (0.50) | TDP1MAPTCLCN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |