Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18529850 | 0.86 | TDP1 (0.52) | TDP1MAPTALDH1A1CLCN2KDM4E | |
| SCHEMBL31346670 | 0.85 | MAPT (0.51) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7032033 | 0.85 | MAPT (0.51) | TDP1MAPTPDE4DPOLBMAPK1 | |
| SCHEMBL6931814 | 0.85 | TDP1 (0.55) | TDP1MAPTALDH1A1CLCN2KDM4E | |
| SCHEMBL30949565 | 0.85 | TDP1 (0.55) | TDP1MAPTALDH1A1CLCN2KDM4E | |
| SCHEMBL10407306 | 0.84 | TDP1 (0.50) | TDP1MAPTKDM4EPDE4DHTT | |
| SCHEMBL17063591 | 0.83 | ALDH1A1 (0.61) | TDP1MAPTALDH1A1CLCN2KDM4E | |
| SCHEMBL7693236 | 0.82 | TDP1 (0.50) | TDP1MAPTALDH1A1CLCN2KDM4E | |
| SCHEMBL102827 | 0.82 | MAPT (0.72) | TDP1MAPTALDH1A1KDM4EPDE4D | |
| SCHEMBL27978300 | 0.82 | MAPT (0.60) | TDP1MAPTALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092083-A1 | VANCOMYCIN DERIVATIVES WITH SIDEROPHORE MODIFICATION AS NOVEL REPURPOSED ANTIBIOTICS TO COMBAT GRAM-NEGATIVE BACTERIAL INFECTION | RESEARCH TRIANGLE INSTITUTE (US) | 2026-04-02 | — | — | US | disclosed |
| EP-4676533-A1 | VANCOMYCIN DERIVATIVES WITH SIDEROPHORE MODIFICATION AS NOVEL REPURPOSED ANTIBIOTICS TO COMBAT GRAM-NEGATIVE BACTERIAL INFECTION | Research Triangle Institute (US) | 2026-01-14 | — | — | EP | disclosed |
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2025202864-A1 | ENT1 INHIBITORS IN COMBINATION WITH ONCOLYTIC VIRUSES AND THEIR USE IN THE TREATMENT OF CANCER | iTeos Belgium SA (BE) | 2025-10-02 | — | — | WO | disclosed |
| WO-2025124531-A1 | 1, 3-BENZODIOXOL DERIVATIVES AND USES THEREOF | GEWU BIO CO., LTD (CN) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025104613-A1 | ENT1 INHIBITORS IN COMBINATION WITH CHECKPOINT INHIBITORS | iTeos Belgium SA (BE) | 2025-05-22 | — | — | WO | disclosed |
| CN-119390668-A | Compound with ketoxime ether structure and application thereof | 复旦大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-115867535-B | Substituted benzamides as modulators of TREX1 | 星座制药公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2024191690-A1 | VANCOMYCIN DERIVATIVES WITH SIDEROPHORE MODIFICATION AS NOVEL REPURPOSED ANTIBIOTICS TO COMBAT GRAM-NEGATIVE BACTERIAL INFECTION | RESEARCH TRIANGLE INSTITUTE (US) | 2024-09-19 | — | — | WO | disclosed |
| EP-3997096-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2024-08-28 | — | — | EP | disclosed |
| EP-1368354-A1 | MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Pfizer Products Inc. (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-1093367-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6509366-B2 | Substituted imidazoles as selective modulators of Bradykinin B2 receptors | NEUROGEN CORPORATION | 2003-01-21 | — | — | US | disclosed |
| US-20030008893-A1 | Modulators of chemokine receptor activity | COLON-CRUZ ROBERTO (US) | 2003-01-09 | — | — | US | disclosed |
| WO-2002070523-A1 | MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | PFIZER PRODUCTS INC. (US) | 2002-09-12 | — | — | WO | disclosed |
| US-20020115693-A1 | Substituted imidazoles as selective modulators of bradykinin B2 receptors | NEUROGEN CORPORATION | 2002-08-22 | — | — | US | disclosed |
| WO-2001056995-A1 | SUBSTITUTED IMIDAZOLES AS SELECTIVE MODULATORS OF BRADYKININ B2 RECEPTORS | NUEROGEN CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
| EP-1093367-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-04-25 | — | — | EP | disclosed |
| WO-1999066925-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-29 | — | — | WO | disclosed |
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092083-A1 | VANCOMYCIN DERIVATIVES WITH SIDEROPHORE MODIFICATION AS NOVEL REPURPOSED ANTIBIOTICS TO COMBAT GRAM-NEGATIVE BACTERIAL INFECTION | SLC11A2, SLC39A11, SLC39A3 | TDP1 4752/4885MAPT 4839/4885ALDH1A1 2826/4885 |
| US-20030008893-A1 | Modulators of chemokine receptor activity | CCR1, CCR3, CCR2 | TDP1 3700/4885MAPT 4154/4885ALDH1A1 1764/4885 |
| US-20020115693-A1 | Substituted imidazoles as selective modulators of bradykinin B2 receptors | BDKRB2, BDKRB1, KISS1R | TDP1 3822/4885MAPT 3044/4885ALDH1A1 3723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.