Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949532 | 0.82 | PTPN1 (0.39) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21232087 | 0.81 | KDM4E (0.45) | KDM4ENR4A2CA12CA1CA2 | |
| SCHEMBL15987529 | 0.81 | KDM4E (0.45) | KDM4ENR4A2CA12CA1CA2 | |
| SCHEMBL30949553 | 0.76 | CYP1A2 (0.42) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL348258 | 0.74 | KDM4E (0.48) | KDM4ENR4A2CA12CA1CA2 | |
| SCHEMBL29855962 | 0.74 | KDM4E (0.48) | KDM4ENR4A2CA12CA1CA2 | |
| SCHEMBL14745247 | 0.73 | NR4A2 (0.50) | KDM4ENR4A2CA12CA1CA2 | |
| SCHEMBL30949607 | 0.73 | POLB (0.43) | KMT2A | |
| SCHEMBL23800439 | 0.72 | NR4A2 (0.42) | KDM4ENR4A2CA12CA1CA2 | |
| SCHEMBL15822095 | 0.72 | P2RX7 (0.53) | KDM4ENR4A2TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |