SCHEMBL30949532

SCHEMBL30949532

Cn1ccc2c(C(=O)O)c(Br)ccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.39
EGFR P00533 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MCL1 Q07820 1/20 0.35
KDM4E B2RXH2 4/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33
TUBB8 Q3ZCM7 1/20 0.33
TUBA3E Q6PEY2 1/20 0.33
TUBA1A Q71U36 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30949569 0.82 KDM4E (0.45) EGFRKMT2AKDM4EALDH1A1MAPT
SCHEMBL5361046 0.81 PTPN1 (0.40) PTPN1EGFRL3MBTL1KDM4EALDH1A1
SCHEMBL15999069 0.77 CA12 (0.49) PTPN1EGFRMEN1KMT2AL3MBTL1
SCHEMBL30949607 0.73 POLB (0.43) MEN1KMT2AP2RX7CNR1CNR2
SCHEMBL30949513 0.73 MEN1 (0.35) EGFRMEN1KMT2AL3MBTL1MCL1
SCHEMBL19100569 0.71 TTR (0.44) PTPN1MCL1KDM4EALDH1A1TUBB4A
SCHEMBL29856013 0.71 TTR (0.44) PTPN1MCL1KDM4EALDH1A1TUBB4A
SCHEMBL15374086 0.71 DHFR (0.44) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL31628177 0.71 RHEB (0.41) KDM4EALDH1A1MAPTRXFP1DHFR
SCHEMBL31735776 0.71 P2RX7 (0.39) KDM4EALDH1A1MAPTRXFP1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4652154-A1 NOVEL ALPK1 INHIBITORS Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) 2025-11-26 EP disclosed
WO-2024153225-A1 NOVEL ALPK1 INHIBITORS PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) 2024-07-25 WO disclosed