Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478188 | 0.76 | TLR8 (0.50) | TLR8KCNH2ARG1 | |
| Bromide SCHEMBL10795216 | 0.76 | TLR8 (0.50) | TLR8KCNH2ARG1TYMPPOLB | |
| SCHEMBL12643820 | 0.74 | — | — | |
| SCHEMBL13099877 | 0.74 | TLR8 (0.58) | TLR8KCNH2ARG1TYMPKMT2A | |
| Hydrochloric Acid SCHEMBL9229553 | 0.72 | — | — | |
| SCHEMBL6102228 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL19970393 | 0.69 | TLR8 (0.76) | TLR8KCNH2ARG1TYMPKMT2A | |
| SCHEMBL4070783 | 0.69 | PKM (0.54) | PKMMTORKDM4ELMNA | |
| SCHEMBL8970561 | 0.69 | ARG1 (0.50) | TLR8KCNH2ARG1TYMPHPGD | |
| SCHEMBL14640235 | 0.69 | ARG1 (0.54) | TLR8KCNH2ARG1TYMPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |