Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25474566 | 0.88 | CYP46A1 (0.57) | CYP46A1SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL12192433 | 0.85 | ALDH1A1 (0.51) | SLC6A4SLC6A3NPC1RAB9AKMT2A | |
| SCHEMBL30876354 | 0.84 | SLC6A3 (0.65) | SLC6A4SLC6A3NPC1RAB9AKMT2A | |
| SCHEMBL27324419 | 0.84 | SLC6A3 (0.65) | SLC6A4SLC6A3NPC1RAB9AKMT2A | |
| SCHEMBL29706660 | 0.84 | GAA (0.50) | SLC6A4SLC6A3NPC1RAB9AKMT2A | |
| SCHEMBL24390973 | 0.83 | CYP46A1 (0.56) | CYP46A1SLC6A4SLC6A3HSD17B10MAPT | |
| SCHEMBL2313764 | 0.82 | ALDH1A1 (0.46) | SLC6A4SLC6A3NPC1RAB9AKMT2A | |
| SCHEMBL6838053 | 0.82 | BDKRB1 (0.50) | CYP46A1HSD17B10 | |
| SCHEMBL2313608 | 0.81 | HPGD (0.51) | SLC6A4SLC6A3NPC1RAB9AKMT2A | |
| SCHEMBL30313770 | 0.81 | KDM4E (0.55) | CYP46A1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |