SCHEMBL30950508

SCHEMBL30950508

N#Cc1cccc(Br)c1C(F)F

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.41
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HTT P42858 1/20 0.31
MCL1 Q07820 1/20 0.31
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26349030 0.80 DYRK1A (0.41) DYRK1ATSHRLMNACA1CA2
SCHEMBL27367559 0.78 DYRK1A (0.40) DYRK1ATSHRLMNACA1CA2
SCHEMBL1770665 0.78 ALDH1A1 (0.33) CA1CA2
SCHEMBL8576407 0.77 TDP1 (0.36) DYRK1A
SCHEMBL12490213 0.77 DYRK1A (0.39) DYRK1ATSHRLMNACA1CA2
SCHEMBL21811832 0.74 CYP11B1 (0.36)
SCHEMBL8574987 0.74 CYP11B1 (0.33) DYRK1A
SCHEMBL977135 0.72 DYRK1A (0.44) DYRK1ATSHRLMNACA1CA2
SCHEMBL29361902 0.72 DYRK1A (0.44) DYRK1ATSHRLMNACA1CA2
SCHEMBL25300709 0.72 TSHR (0.34) DYRK1ATSHRLMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663626-A1 IMINE COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF Bio Genuine (Shanghai) Biotech Co., Ltd (CN) 2025-12-17 EP disclosed
WO-2024165071-A1 IMINE COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 上海葆正医药科技有限公司 2024-08-15 WO disclosed
WO-2024129395-A1 BTK INHIBITORS GWYNANT THERAPEUTICS, INC. (US) 2024-06-20 WO disclosed