Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26349030 | 0.86 | DYRK1A (0.41) | DYRK1ATSHRLMNAALDH1A1HPGD | |
| SCHEMBL12490213 | 0.83 | DYRK1A (0.39) | DYRK1ATSHRLMNAALDH1A1HPGD | |
| SCHEMBL10830794 | 0.79 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL30950508 | 0.78 | DYRK1A (0.41) | DYRK1ATSHRLMNANPC1RAB9A | |
| SCHEMBL27475655 | 0.78 | POLB (0.45) | TSHRALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL28044155 | 0.77 | GABRA1 (0.39) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL807524 | 0.74 | TSHR (0.46) | TSHRALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL3112611 | 0.74 | NOTUM (0.40) | LMNAALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL27912602 | 0.73 | TDP1 (0.42) | TSHRALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL2885020 | 0.71 | P2RX7 (0.40) | TSHRLMNAALDH1A1HPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052672-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1991-07-03 | — | — | CN | disclosed |