SCHEMBL30951019

SCHEMBL30951019

N#CCC(=O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.64
SRD5A2 P31213 1/20 0.50
CTNNB1 P35222 1/20 0.50
WNT3A P56704 1/20 0.50
POLB P06746 2/20 0.49
ALDH1A1 P00352 2/20 0.49
CTSL P07711 1/20 0.48
LMNA P02545 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
P2RX1 P51575 1/20 0.48
ACHE P22303 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 2/20 0.46
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
MAOB P27338 1/20 0.46
MEN1 O00255 1/20 0.46
KCNK3 O14649 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139194 1.00 CES2 (0.64) CES2SRD5A2CTNNB1WNT3APOLB
SCHEMBL9168508 0.89 CYP1A2 (0.51) CES2MAOB
SCHEMBL8386448 0.84 CES2 (0.56) CES2SRD5A2CTNNB1WNT3APOLB
SCHEMBL23263974 0.84 DHODH (0.50) CES2MAOB
SCHEMBL4306951 0.83 CES2 (0.59) CES2LMNAP2RX1
SCHEMBL397191 0.82 GSK3B (0.50) CES2ACHEHPGDKMT2AMEN1
SCHEMBL5310454 0.82 ALDH1A1 (0.46) CES2POLBALDH1A1MAOB
SCHEMBL30758861 0.81 CES2 (0.69) CES2SRD5A2CTNNB1WNT3APOLB
SCHEMBL1199185 0.80 CES2 (0.54) CES2SRD5A2CTNNB1WNT3APOLB
SCHEMBL1712437 0.80 CES2 (0.67) CES2SRD5A2CTNNB1WNT3APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118398813-A Positive electrode slurry, positive electrode sheet and secondary battery 广东邦普循环科技有限公司 2024-07-26 CN claimed
CN-118812500-A Substituted aryl diketone nitrile compound with herbicidal activity, preparation method and application 东北农业大学 2024-10-22 CN disclosed
CN-118398813-A Positive electrode slurry, positive electrode sheet and secondary battery 广东邦普循环科技有限公司 2024-07-26 CN disclosed