SCHEMBL30951237

SCHEMBL30951237

c1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)c1cc(-n3c4ccccc4c4ccccc43)ccc1n2C1CCCCO1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
MAPT P10636 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CNR2 P34972 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
CDK4 P11802 4/20 0.32
CDK6 Q00534 2/20 0.32
NPY5R Q15761 1/20 0.32
PER2 O15055 1/20 0.32
CRY1 Q16526 1/20 0.32
CRY2 Q49AN0 1/20 0.32
CDK2 P24941 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31658983 1.00 KDM4E (0.37) KDM4EL3MBTL1ATMMAPTMEN1
SCHEMBL31658978 0.83 CYP4F2 (0.36) KDM4EL3MBTL1MAPTMEN1KMT2A
SCHEMBL22618673 0.82 KDM4E (0.44) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL26829115 0.80 ALDH1A1 (0.43) KDM4EL3MBTL1ATMMAPTMEN1
SCHEMBL8540288 0.77 DDB1 (0.36) MAPTMEN1KMT2APOLBNPSR1
SCHEMBL11969974 0.77 POLB (0.36) KDM4EL3MBTL1MAPTMEN1KMT2A
SCHEMBL25499943 0.77 KDM4E (0.46) KDM4EL3MBTL1ATMMAPTMEN1
SCHEMBL20540673 0.76 PDE10A (0.35) KDM4EATMMEN1KMT2APOLB
SCHEMBL30414897 0.74 MEN1 (0.34) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL29010536 0.74 MEN1 (0.34) KDM4EMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190901-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190901-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 KDM4E 1913/4885L3MBTL1 707/4885ATM 3294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.