Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951345 | 0.82 | TDP1 (0.35) | TDP1 | |
| SCHEMBL30951445 | 0.75 | TDP1 (0.41) | TDP1 | |
| SCHEMBL21752097 | 0.75 | TDP1 (0.41) | TDP1 | |
| SCHEMBL10846450 | 0.74 | TDP1 (0.44) | TDP1 | |
| SCHEMBL15884262 | 0.73 | TDP1 (0.40) | TDP1MEN1KMT2A | |
| SCHEMBL23748091 | 0.72 | TDP1 (0.39) | TDP1 | |
| SCHEMBL30951365 | 0.72 | TDP1 (0.39) | TDP1 | |
| SCHEMBL28834293 | 0.71 | TDP1 (0.39) | TDP1MEN1KMT2A | |
| SCHEMBL2767989 | 0.70 | TDP1 (0.38) | TDP1KMT2A | |
| SCHEMBL30310964 | 0.70 | TDP1 (0.38) | TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094150-A1 | NLRP3 INFLAMMASOME INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-05-10 | — | — | WO | disclosed |