Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834366 | 0.75 | MAPT (0.35) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL15884262 | 0.73 | TDP1 (0.40) | TDP1ALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL28834317 | 0.73 | IDO1 (0.35) | ALDH1A1LMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL11903960 | 0.72 | TDP1 (0.39) | TDP1ALDH1A1KMT2ACYP1A2MEN1 | |
| SCHEMBL30951401 | 0.71 | TDP1 (0.35) | TDP1KMT2AMEN1 | |
| SCHEMBL14114863 | 0.71 | ALDH1A1 (0.42) | TDP1ALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL10846450 | 0.70 | TDP1 (0.44) | TDP1ALDH1A1PKM | |
| SCHEMBL5377910 | 0.70 | TDP1 (0.50) | TDP1ALDH1A1PKM | |
| SCHEMBL29404355 | 0.70 | TDP1 (0.44) | TDP1ALDH1A1LMNAL3MBTL1PKM | |
| SCHEMBL1188816 | 0.70 | TDP1 (0.44) | TDP1ALDH1A1LMNAL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981256-A | Single-ring agonists of the interferon gene stimulator STING | 斯克里普斯研究学院 | 2022-08-30 | — | — | CN | disclosed |