Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254456 | 1.00 | DYRK1A (0.47) | DYRK1ADYRK1BPDE4APDE4BPDE4C | |
| SCHEMBL30951527 | 0.85 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL29254459 | 0.85 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL29254435 | 0.77 | GABRA1 (0.50) | MAPTKDM4ELMNAMAPK1GABRA1 | |
| SCHEMBL30951512 | 0.77 | PDE4A (0.54) | DYRK1ADYRK1BPDE4APDE4BPDE4C | |
| SCHEMBL29254461 | 0.77 | PDE4A (0.54) | DYRK1ADYRK1BPDE4APDE4BPDE4C | |
| SCHEMBL4842001 | 0.74 | PDE4A (0.73) | DYRK1ADYRK1BPDE4APDE4BPDE4C | |
| SCHEMBL29930898 | 0.70 | DYRK1A (0.65) | DYRK1ADYRK1BKIT | |
| SCHEMBL30951522 | 0.69 | MAPT (0.63) | PDE4APDE4BPDE4CPDE4DMAPT | |
| Hydrochloric Acid SCHEMBL30951578 | 0.68 | MAPT (0.62) | PDE4APDE4BPDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076605-A | Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof | 洛蒙治疗公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118076605-A | Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof | 洛蒙治疗公司 | 2024-05-24 | — | — | CN | disclosed |