Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | LITAF | Q99732 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254461 | 1.00 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL30951527 | 0.84 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DPDGFRA | |
| SCHEMBL29254459 | 0.84 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DPDGFRA | |
| SCHEMBL29254453 | 0.78 | ATP4A (0.41) | TNFLITAFKDM4EALDH1A1HPGDS | |
| SCHEMBL30951531 | 0.77 | DYRK1A (0.47) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL29254456 | 0.77 | DYRK1A (0.47) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL5246987 | 0.71 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL6477699 | 0.70 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL1407521 | 0.69 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL30345130 | 0.69 | ALDH1A1 (0.54) | RETKDM4EHSD17B10ALDH1A1ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076605-A | Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof | 洛蒙治疗公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118076605-A | Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof | 洛蒙治疗公司 | 2024-05-24 | — | — | CN | disclosed |