SCHEMBL30951561

SCHEMBL30951561

COC(=O)Nc1nc2cc(C(=O)c3ccccc3F)ccc2[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.61
▸ KDR P35968 3/20 0.61
▸ CYP1A2 P05177 3/20 0.61
▸ ALDH1A1 P00352 3/20 0.61
▸ ABL1 P00519 2/20 0.61
▸ CYP2C9 P11712 2/20 0.61
▸ HTT P42858 2/20 0.61
▸ HIF1A Q16665 2/20 0.61
▸ ABCC4 O15439 1/20 0.61
▸ USP2 O75604 1/20 0.61
▸ MAPK1 P28482 2/20 0.60
▸ ADORA3 P0DMS8 1/20 0.60
▸ PTGS1 P23219 1/20 0.60
▸ RXFP1 Q9HBX9 1/20 0.60
▸ RAF1 P04049 5/20 0.60
▸ BRAF P15056 5/20 0.60
▸ NPC1 O15118 4/20 0.55
▸ TP53 P04637 3/20 0.55
▸ PKM P14618 2/20 0.55
▸ GAA P10253 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1466710 0.89 RAF1 (0.66) LMNAKDRCYP1A2ALDH1A1ABL1
SCHEMBL1466448 0.89 RAF1 (0.67) LMNAKDRCYP1A2ALDH1A1ABL1
Mebendazole SCHEMBL3429179 0.86 ABL1 (0.82) LMNAKDRCYP1A2ALDH1A1ABL1
Mebendazole SCHEMBL15860 0.86 ABL1 (0.82) LMNAKDRCYP1A2ALDH1A1ABL1
Mebendazole SCHEMBL29409261 0.86 ABL1 (0.82) LMNAKDRCYP1A2ALDH1A1ABL1
Flubendazole SCHEMBL8005889 0.85 KDR (0.76) LMNAKDRCYP1A2ALDH1A1ABL1
Mebendazole SCHEMBL17262440 0.85 ABL1 (0.80) LMNAKDRCYP1A2ALDH1A1ABL1
Mebendazole SCHEMBL21051203 0.85 ABL1 (0.80) LMNAKDRCYP1A2ALDH1A1ABL1
Mebendazole SCHEMBL21051200 0.85 ABL1 (0.80) LMNAKDRCYP1A2ALDH1A1ABL1
Flubendazole SCHEMBL29409278 0.85 KDR (0.82) LMNAKDRCYP1A2ALDH1A1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4389116-B1 PHARMACEUTICAL AQUEOUS FLUBENDAZOLE SUSPENSION DECHRA LTD (GB) 2025-09-10 — — EP disclosed
EP-4389116-A1 PHARMACEUTICAL AQUEOUS FLUBENDAZOLE SUSPENSION Dechra Ltd (GB) 2024-06-26 — — EP disclosed
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