SCHEMBL30951963

SCHEMBL30951963

NS(=O)(=O)c1ccc(C2(O)C(=O)N(Cc3ccc(OC(F)F)cc3)c3ccccc32)cc1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 16/20 0.57
CHRM5 P08912 1/20 0.43
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30951950 0.87 SCN9A (0.76) SCN9ACHRM5
SCHEMBL30951949 0.87 SCN9A (0.76) SCN9ACHRM5
SCHEMBL30951997 0.86 SCN9A (0.62) SCN9A
SCHEMBL30951993 0.86 SCN9A (0.62) SCN9A
SCHEMBL30951988 0.84 SCN9A (0.60) SCN9A
SCHEMBL30951992 0.81 SCN9A (0.56) SCN9AMAPT
SCHEMBL30951989 0.81 SCN9A (0.65) SCN9AMAPT
SCHEMBL30951998 0.81 SCN9A (0.56) SCN9A
SCHEMBL30951999 0.80 SCN9A (0.54) SCN9A
SCHEMBL30951971 0.77 CNR1 (0.51) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630401-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF Rutgers, the State University of New Jersey (US) 2025-10-15 EP disclosed
WO-2024124023-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-06-13 WO disclosed