Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | CA2 | P00918 | 9/20 | 0.48 |
| ▸ | CA9 | Q16790 | 8/20 | 0.48 |
| ▸ | CA12 | O43570 | 7/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951961 | 0.87 | SCN9A (0.55) | CA1CA2CA9CA12SCN9A | |
| SCHEMBL30951997 | 0.86 | SCN9A (0.62) | CA1CA2CA9CA12SCN9A | |
| SCHEMBL30951993 | 0.86 | SCN9A (0.62) | CA1CA2CA9CA12SCN9A | |
| SCHEMBL30951991 | 0.82 | CNR1 (0.48) | CA1CA2CA9CA12 | |
| SCHEMBL30951955 | 0.76 | PTGS2 (0.43) | CA1CA2CA9CA12MAPT | |
| SCHEMBL30951988 | 0.75 | SCN9A (0.60) | CA1CA2CA9CA12SCN9A | |
| SCHEMBL30951989 | 0.74 | SCN9A (0.65) | SCN9AMAPTTP53 | |
| SCHEMBL30951949 | 0.72 | SCN9A (0.76) | CA1CA2CA9CA12SCN9A | |
| SCHEMBL30951992 | 0.72 | SCN9A (0.56) | CA1CA2CA9CA12SCN9A | |
| SCHEMBL30951998 | 0.72 | SCN9A (0.56) | SCN9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630401-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | Rutgers, the State University of New Jersey (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024124023-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-06-13 | — | — | WO | disclosed |