Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.35 |
| ▸ | PRKCG | P05129 | 4/20 | 0.35 |
| ▸ | PRKCB | P05771 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | PRKCA | P17252 | 4/20 | 0.35 |
| ▸ | PRKCH | P24723 | 4/20 | 0.35 |
| ▸ | PRKCI | P41743 | 4/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951972 | 0.85 | CA2 (0.38) | NAMPTP2RX7PRKD3PRKCGPRKCB | |
| SCHEMBL30951946 | 0.85 | CYP2C9 (0.36) | NAMPTALDH1A1CYP3A4CYP2D6LMNA | |
| SCHEMBL30951953 | 0.85 | MAPK10 (0.39) | NAMPTALDH1A1CYP2D6LMNAMAPK10 | |
| SCHEMBL30951986 | 0.82 | SCN9A (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL30951948 | 0.79 | BRD4 (0.42) | NAMPTALDH1A1KIF18AMEN1KMT2A | |
| SCHEMBL30951952 | 0.69 | SCN9A (0.53) | ALDH1A1P2RX7 | |
| SCHEMBL30951940 | 0.69 | SCN9A (0.40) | MEN1KMT2AIDO1KDM4E | |
| SCHEMBL30951947 | 0.69 | IDO1 (0.39) | IDO1 | |
| SCHEMBL30951978 | 0.69 | SCN9A (0.43) | ALDH1A1IDO1KDM4E | |
| SCHEMBL5000637 | 0.68 | PRKD3 (0.63) | P2RX7PRKD3PRKCGPRKCBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630401-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | Rutgers, the State University of New Jersey (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024124023-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-06-13 | — | — | WO | disclosed |