Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.46 |
| ▸ | GRM5 | P41594 | 6/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24319286 | 0.90 | GRM1 (0.47) | NAMPTGRM1GRM5PDK4DDB1 | |
| SCHEMBL31201927 | 0.86 | PDK4 (0.46) | NAMPTGRM1GRM5PDK4DDB1 | |
| SCHEMBL29223732 | 0.86 | PDK4 (0.46) | NAMPTGRM1GRM5PDK4DDB1 | |
| SCHEMBL23120656 | 0.86 | NAMPT (0.52) | NAMPTGRM1GRM5PDK4DDB1 | |
| SCHEMBL29264345 | 0.86 | DDB1 (0.47) | DDB1CRBN | |
| SCHEMBL29223716 | 0.86 | SCN9A (0.47) | NAMPTGRM1GRM5PDK4DDB1 | |
| SCHEMBL25167744 | 0.83 | PDK4 (0.51) | NAMPTGRM1GRM5PDK4DDB1 | |
| SCHEMBL30913581 | 0.83 | PDK4 (0.51) | NAMPTGRM1GRM5PDK4DDB1 | |
| SCHEMBL23538393 | 0.81 | DDB1 (0.53) | NAMPTGRM1GRM5PDK4DDB1 | |
| SCHEMBL27167732 | 0.81 | NAMPT (0.43) | NAMPTGRM1GRM5PDK4CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271284-A | Estrogen receptor modulators and uses thereof | 江苏威凯尔医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |