Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 10/20 | 0.37 |
| ▸ | TDO2 | P48775 | 10/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101188 | 0.86 | IDO1 (0.38) | BRD4IDO1TDO2PTGS2CYP1A1 | |
| SCHEMBL3093911 | 0.85 | CYP2A6 (0.34) | PTGS2PTGESC3AR1CYP1A1CYP1A2 | |
| SCHEMBL3089943 | 0.83 | IDO1 (0.45) | BRD4IDO1TDO2CYP1A1CYP1A2 | |
| SCHEMBL3109648 | 0.82 | BRD4 (0.39) | BRD4IDO1TDO2CYP1A2 | |
| SCHEMBL3113043 | 0.79 | ALDH1A1 (0.39) | BRD4IDO1TDO2CYP1A2 | |
| SCHEMBL3106845 | 0.79 | IDO1 (0.46) | BRD4IDO1TDO2 | |
| SCHEMBL3090921 | 0.79 | BRD4 (0.37) | BRD4IDO1TDO2PTGS2PTGES | |
| SCHEMBL3095541 | 0.78 | ALDH1A1 (0.40) | BRD4IDO1TDO2CYP1A2 | |
| SCHEMBL3104373 | 0.77 | BRD4 (0.36) | BRD4IDO1TDO2PTGS2 | |
| SCHEMBL3106796 | 0.77 | NPC1 (0.40) | BRD4IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210876-B1 | HETEROCYCLIC COMPOUND AS GLUCAGON ANTAGONIST | TAKEDA PHARMACEUTICAL (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-8309580-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20100256156-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2210876-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256156-A1 | HETEROCYCLIC COMPOUND | GLP1R, GPR119, GCGR | BRD4 90/4885IDO1 1206/4885TDO2 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.