Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596321 | 0.81 | RXFP1 (0.72) | BCAT2RXFP1KMT2AALDH1A1NPSR1 | |
| SCHEMBL2980845 | 0.80 | BCAT2 (0.68) | BCAT2RXFP1KMT2AALDH1A1NPSR1 | |
| SCHEMBL9121778 | 0.80 | BCAT2 (0.72) | BCAT2RXFP1KMT2AALDH1A1GABRA1 | |
| SCHEMBL1670982 | 0.80 | BCAT2 (0.72) | BCAT2RXFP1KMT2AALDH1A1NPSR1 | |
| SCHEMBL6229196 | 0.79 | GABRA1 (0.67) | BCAT2RXFP1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4445671 | 0.77 | BCAT2 (1.00) | BCAT2RXFP1KMT2AALDH1A1HPGD | |
| SCHEMBL27688626 | 0.76 | BCAT2 (0.62) | BCAT2RXFP1KMT2AALDH1A1GABRA1 | |
| Hydrochloric Acid SCHEMBL31228833 | 0.75 | BCAT2 (0.96) | BCAT2RXFP1KMT2AALDH1A1HPGD | |
| SCHEMBL9394563 | 0.75 | BCAT2 (0.66) | BCAT2RXFP1KMT2AALDH1A1TSHR | |
| SCHEMBL4911370 | 0.73 | KDM4E (0.67) | RXFP1KMT2AALDH1A1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121709-A1 | PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS | PFIZER INC. (US) | 2024-06-13 | — | — | WO | disclosed |