Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27322464 | 0.94 | WNT1 (0.43) | WNT1GSK3BDYRK1AIRAK4RIPK2 | |
| SCHEMBL24731399 | 0.90 | WNT1 (0.41) | WNT1GSK3BDYRK1AIRAK4RIPK2 | |
| SCHEMBL24731397 | 0.90 | WNT1 (0.41) | WNT1GSK3BDYRK1AIRAK4RIPK2 | |
| SCHEMBL31218177 | 0.90 | KIT (0.41) | WNT1GSK3BDYRK1AIRAK4RIPK2 | |
| SCHEMBL31217995 | 0.90 | CLK1 (0.43) | WNT1GSK3BDYRK1AIRAK4RIPK2 | |
| SCHEMBL24731567 | 0.90 | CLK1 (0.43) | WNT1GSK3BDYRK1AIRAK4RIPK2 | |
| SCHEMBL24731977 | 0.90 | KIT (0.41) | WNT1GSK3BDYRK1AIRAK4RIPK2 | |
| SCHEMBL31001469 | 0.89 | WNT1 (0.40) | WNT1GSK3BDYRK1AIRAK4RIPK2 | |
| SCHEMBL30952659 | 0.88 | RET (0.45) | — | |
| SCHEMBL30952662 | 0.88 | RET (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121709-A1 | PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS | PFIZER INC. (US) | 2024-06-13 | — | — | WO | disclosed |