Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 7/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952659 | 1.00 | RET (0.45) | RETLRRK2GPR119METMEN1 | |
| SCHEMBL30952686 | 1.00 | RET (0.45) | RETLRRK2GPR119METMEN1 | |
| SCHEMBL30083205 | 0.90 | RET (0.44) | RETLRRK2GPR119MAPTSMN1; SMN2 | |
| SCHEMBL30083171 | 0.89 | RET (0.46) | RETLRRK2GPR119 | |
| SCHEMBL30952656 | 0.88 | WNT1 (0.40) | — | |
| SCHEMBL30952660 | 0.88 | LMNA (0.44) | GPR119MEN1MAPTTSHRKMT2A | |
| SCHEMBL30952749 | 0.87 | RET (0.42) | RETLRRK2GPR119 | |
| SCHEMBL31019186 | 0.83 | RET (0.43) | RETLRRK2GPR119MET | |
| SCHEMBL30083142 | 0.82 | BACE1 (0.45) | GPR119MEN1MAPTTSHRKMT2A | |
| SCHEMBL27322464 | 0.82 | WNT1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121709-A1 | PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS | PFIZER INC. (US) | 2024-06-13 | — | — | WO | disclosed |