SCHEMBL30952956

SCHEMBL30952956

CC1CCC([C@H](NC(=O)OC(C)(C)C)C(=O)Nc2cc(CN3C[C@@H](C(F)(F)F)NC3=O)ccn2)CC1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ AAK1 Q2M2I8 4/20 0.40
▸ IGF1R P08069 1/20 0.38
▸ IL17A Q16552 3/20 0.33
▸ MMP1 P03956 1/20 0.33
▸ SCN9A Q15858 2/20 0.33
▸ CDK5 Q00535 3/20 0.32
▸ DYRK1A Q13627 3/20 0.32
▸ CDK5R1 Q15078 3/20 0.32
▸ PSEN1 P49768 1/20 0.32
▸ PSEN2 P49810 1/20 0.32
▸ APH1B Q8WW43 1/20 0.32
▸ NCSTN Q92542 1/20 0.32
▸ APH1A Q96BI3 1/20 0.32
▸ PSENEN Q9NZ42 1/20 0.32
▸ NR3C2 P08235 2/20 0.31
▸ RIPK3 Q9Y572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953528 0.93 AAK1 (0.39) AAK1IGF1RIL17AMMP1SCN9A
SCHEMBL30952974 0.91 IL17A (0.42) AAK1IGF1RIL17AMMP1SCN9A
SCHEMBL30953002 0.91 AAK1 (0.42) AAK1IGF1RMMP1SCN9ACDK5
SCHEMBL30953154 0.88 CTSL (0.34) NR3C2
SCHEMBL30952986 0.88 IGF1R (0.39) AAK1IGF1RIL17ASCN9ACDK5
SCHEMBL30953157 0.87 IL17A (0.39) IGF1RIL17APSEN1PSEN2APH1B
SCHEMBL30953126 0.86 AAK1 (0.39) AAK1IL17AMMP1SCN9APSEN1
SCHEMBL30953226 0.85 NR3C2 (0.37) IGF1RIL17ACDK5DYRK1ACDK5R1
Hydrochloric Acid SCHEMBL30953230 0.84 NR3C2 (0.36) IGF1RIL17ACDK5DYRK1ACDK5R1
SCHEMBL30953266 0.84 AAK1 (0.38) AAK1IL17AMMP1SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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