SCHEMBL30952986

SCHEMBL30952986

CC(C)(C)OC(=O)N[C@H](C(=O)Nc1cc(CN2C[C@@H](C(F)(F)F)NC2=O)ccn1)C(C1CC1)C1CC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ IGF1R P08069 1/20 0.39
▸ IL17A Q16552 3/20 0.36
▸ SCN9A Q15858 3/20 0.33
▸ AAK1 Q2M2I8 2/20 0.33
▸ BACE1 P56817 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ EGFR P00533 1/20 0.33
▸ CDK5 Q00535 3/20 0.32
▸ DYRK1A Q13627 3/20 0.32
▸ CDK5R1 Q15078 3/20 0.32
▸ NR3C2 P08235 2/20 0.32
▸ RIPK3 Q9Y572 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30952956 0.88 AAK1 (0.40) IGF1RIL17ASCN9AAAK1CDK5
SCHEMBL30952974 0.85 IL17A (0.42) IGF1RIL17ASCN9AAAK1CDK5
SCHEMBL30952940 0.84 IL17A (0.39) IL17ANR3C2
SCHEMBL30952968 0.84 IL17A (0.46) IGF1RIL17ANR3C2
SCHEMBL30953412 0.83 IGF1R (0.38) IGF1RSCN9AAAK1CYP3A4EGFR
SCHEMBL30953414 0.83 IGF1R (0.38) IGF1RSCN9AAAK1CYP3A4EGFR
SCHEMBL30953019 0.83 IL17A (0.47) IL17ANR3C2
Hydrochloric Acid SCHEMBL30953252 0.82 NR3C2 (0.37) IL17ACDK5DYRK1ACDK5R1NR3C2
SCHEMBL30953236 0.81 CDK5 (0.40) IGF1RAAK1CDK5DYRK1ACDK5R1
SCHEMBL30953226 0.80 NR3C2 (0.37) IGF1RIL17ACDK5DYRK1ACDK5R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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