SCHEMBL30952984

SCHEMBL30952984

Cn1nccc1C(=O)N[C@H](C(=O)Nc1cc(CNC(=O)CCC(F)(F)F)ccn1)C(C1CC1)C1CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 2/20 0.37
▸ KMT2A Q03164 2/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ GSK3B P49841 2/20 0.36
▸ DYRK1A Q13627 2/20 0.36
▸ CTSS P25774 1/20 0.35
▸ LMNA P02545 1/20 0.34
▸ MMP13 P45452 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ TP53 P04637 1/20 0.34
▸ TAS1R3 Q7RTX0 1/20 0.33
▸ TAS1R1 Q7RTX1 1/20 0.33
▸ TAS1R2 Q8TE23 1/20 0.33
▸ CDK2 P24941 1/20 0.33
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ NR3C2 P08235 2/20 0.33
▸ PKM P14618 1/20 0.33
▸ MBOAT4 Q96T53 1/20 0.33
▸ MAPK13 O15264 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30952958 0.88 IL17A (0.37) IL17AKMT2AL3MBTL1GSK3BDYRK1A
SCHEMBL30953481 0.87 GSK3B (0.37) IL17AKMT2AL3MBTL1GSK3BDYRK1A
SCHEMBL30953409 0.82 CYP3A4 (0.40) KMT2AGSK3BCTSSMEN1CDK2
SCHEMBL30953405 0.82 CYP3A4 (0.40) KMT2AGSK3BCTSSMEN1CDK2
SCHEMBL30952940 0.79 IL17A (0.39) IL17AKMT2AL3MBTL1GSK3BTAS1R3
SCHEMBL30953025 0.78 IL17A (0.47) IL17AGSK3BDYRK1ANR3C2MAPK14
SCHEMBL30953046 0.77 IL17A (0.38) IL17AKMT2AL3MBTL1GSK3BCTSS
SCHEMBL30953100 0.74 GSK3B (0.36) KMT2AL3MBTL1GSK3BDYRK1ACTSS
SCHEMBL30952964 0.73 CTSS (0.37) IL17AGSK3BDYRK1ACTSSCDK2
SCHEMBL25563201 0.70 IL17A (0.41) IL17AKMT2AL3MBTL1GSK3BCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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