SCHEMBL30952940

SCHEMBL30952940

Cn1nccc1C(=O)N[C@H](C(=O)Nc1cc(CN2C[C@@H](C(F)(F)F)NC2=O)ccn1)C(C1CC1)C1CC1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 4/20 0.39
▸ CDK2 P24941 4/20 0.33
▸ KMT2A Q03164 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ CCNE1 P24864 3/20 0.32
▸ GSK3B P49841 3/20 0.32
▸ TAS1R3 Q7RTX0 1/20 0.31
▸ TAS1R1 Q7RTX1 1/20 0.31
▸ TAS1R2 Q8TE23 1/20 0.31
▸ F11 P03951 1/20 0.31
▸ NR3C2 P08235 1/20 0.31
▸ MBOAT4 Q96T53 1/20 0.31
▸ NPC1 O15118 2/20 0.31
▸ RAB9A P51151 2/20 0.31
▸ MAPK13 O15264 1/20 0.31
▸ MAPK14 Q16539 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ BUB1 O43683 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953019 0.91 IL17A (0.47) IL17ANR3C2MAPK14
SCHEMBL30953046 0.89 IL17A (0.38) IL17ACDK2KMT2AL3MBTL1CCNE1
SCHEMBL30952976 0.88 IL17A (0.36) IL17ACDK2CCNE1GSK3BF11
SCHEMBL30953017 0.88 IL17A (0.36) IL17ACDK2KMT2AL3MBTL1CCNE1
SCHEMBL30952968 0.86 IL17A (0.46) IL17ANR3C2MAPK14
SCHEMBL30952938 0.86 IL17A (0.45) IL17ACDK2CCNE1GSK3BF11
SCHEMBL30952986 0.84 IGF1R (0.39) IL17ANR3C2
SCHEMBL30953083 0.84 IL17A (0.34) IL17ACDK2CCNE1GSK3BTAS1R3
SCHEMBL30952967 0.83 IL17A (0.53) IL17A
SCHEMBL30953308 0.83 IL17A (0.33) IL17ACDK2CCNE1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
Send feedback