SCHEMBL30952993

SCHEMBL30952993

COc1ccc(CC(=O)NCC(N)=O)cn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
LMNA P02545 3/20 0.49
NPC1 O15118 2/20 0.49
PKM P14618 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
NNMT P40261 2/20 0.48
KDM4E B2RXH2 2/20 0.45
MAPT P10636 1/20 0.45
MKNK1 Q9BUB5 1/20 0.43
MKNK2 Q9HBH9 1/20 0.43
NAMPT P43490 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
CCNE1 P24864 2/20 0.41
CDK2 P24941 2/20 0.41
GSK3B P49841 1/20 0.41
CHRM4 P08173 1/20 0.40
MLLT1 Q03111 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29590839 0.84 NNMT (0.57) MEN1KMT2ALMNANPC1PKM
SCHEMBL2371616 0.84 NNMT (0.57) MEN1KMT2ALMNANPC1PKM
SCHEMBL2495046 0.82 MEN1 (0.55) MEN1KMT2ALMNANPC1PKM
Hydrochloric Acid SCHEMBL29629381 0.82 NNMT (0.56) MEN1KMT2ALMNANPC1PKM
SCHEMBL14274253 0.78 HTT (0.65) MEN1KMT2ALMNANPC1SMN1; SMN2
SCHEMBL30195950 0.77 NPC1 (0.51) MEN1KMT2ALMNANPC1PKM
SCHEMBL2492499 0.77 NPC1 (0.51) MEN1KMT2ALMNANPC1PKM
SCHEMBL27596803 0.77 NAMPT (0.53) MEN1KMT2ALMNANPC1PKM
Hydrazine SCHEMBL4704048 0.76 GABRP (0.57) MEN1KMT2ALMNANPC1PKM
SCHEMBL2491663 0.76 GABRP (0.56) MEN1KMT2ALMNANPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 WO disclosed